Test
5-Azacytidine is an analog of the nucleoside cytidine which can be incorporated into DNA and RNA. 5-Azacytidine acts as an epigenetic modifier by incorporating into DNA where it irreversibly binds to DNA methyltransferases, thus inhibiting their activity. REPROGRAMMING· Increases reprogramming efficiency of mouse fibroblasts to induced pluripotent stem (iPS) cells by inducing full reprogramming of partially reprogrammed cells (Mikkelsen et al.).· Resets epigenetic memory in mouse iPS cells, in combination with Trichostatin A (Kim et al.). DIFFERENTIATION· Enhances differentiation to cardiomyocytes from human embryonic stem cells (Yoon et al.).CANCER RESEARCH· Wide range of anti-metabolic activities when tested against cultured cancer cells and an effective chemotherapeutic agent for acute myelogenous leukemia
N6-Benzyladenosine, 4294-16-0, MFCD00005740, 5G
Xanthosine-8-3H 1mCi in sterile water, 1 mCi/ml, S.A. 5-10 Ci/mmol, M.W. 152.1, Exclusive
Medchem Express / Deoxypseudouridine / 1mg / 446257504 / HY-101970 / / 39967-60-7 / [null] / 228.204 / C9H12N2O5
Medchemexpress, HY-10586 200mg 5-Azacytidine CAS:320-67-2 5-Azacytidine (Azacitidine; 5-AzaC; Ladakamycin) is a nucleoside analogue of cytidine that specifically inhibits DNA methylation. 5-Azacytidine is incorporated into DNA to covalently trap DNA methyltransferases and contributes to reverse epigenetic changes[2]. 5-Azacytidine induces cell autophagy[4]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Uridine is one of the five nucleosides used for RNA synthesis and as a building block for other biomolecules (Tsukimoto). Uridine 5’-diphosphate and uridine 5’-triphosphate are signaling molecules that activate the purinergic receptors (Tsukimoto). Uridine is also used as a medium supplement for culturing primary hippocampal neuron cells (François-Moutal et al.).CANCER RESEARCH· Uridine has been used to reduce 5-fluorouracil toxicity, without affecting its antitumor activity (Pizzorno et al.).
50-114-3044 EDU 5-ETHYNYL-2-DEOXYUR 500
Cytidine 5'-diphosphocholine sodium salt dihydrate ~98%, from yeast, solid | Purity: ~98% | Mol Wt: 546.34 | 33818-15-4 | MFCD00150508 | 1G