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LIN28 1632, >98%, Tocris Bioscience™
RNA binding protein Lin28 inhibitor; promotes mESC differentiation; also bromodomain inhibitor
$251.72 - $1075.32
Specifications
| Chemical Name or Material | N-Methyl-N-[3-(3-methyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)phenyl]acetamide |
|---|---|
| CAS | 108825-65-6 |
| Purity Grade Notes | >98% |
| Linear Formula | C15H15N5O |
| Solubility Information | Soluble to 100mM in DMSO and to 100mM in ethanol |
Description
RNA binding protein Lin28 inhibitor (IC50 = 8 μM). Blocks binding of Lin28 to let-7 pre-micro RNA. Inhibits stemness and induces differentiation of murine ESCs. Inhibits growth of tumor cell lines and tumor-sphere formation in vitro. Also bromodomain inhibitor.Specifications
| N-Methyl-N-[3-(3-methyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)phenyl]acetamide | |
| >98% | |
| Soluble to 100mM in DMSO and to 100mM in ethanol |
| 108825-65-6 | |
| C15H15N5O | |
| 281.31 |
Safety and Handling
Recommended Storage : Store at 4°C
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