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Tocris Bioscience™ NS 9283

Positive allosteric modulator of α4β2 nAChRs

Supplier:  Tocris Bioscience™ 5112/50

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Catalog No. 51-125-0


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Description

Description

NS 9283 is a positive allosteric modulator of α4β2 receptor; increases the potency of Ach-evoked currents ∼60 fold without affecting the maximum efficacy (HEK293-hα4β2 cells). Reduces the rate of recovery from desensitization and slows the rate of deactivation. Displays a synergistic effect on the Emax when given with NS206 at 3α:2β receptors.
Specifications

Specifications

>99%
NS 9283
NS 9283
50 mg
248.24
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