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  5. Tocris Bioscience™ MS 436

Tocris Bioscience™ MS 436

Potent and selective BRD4(1) inhibitor

$265.64 - $1081.12

Specifications

Purity >98%
Product Type MS 436
Molecular Weight (g/mol) 383.42
Inhibitors MS 436
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
51-735-0
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Tocris Bioscience™
5173/50 		50 mg
Each for $1,081.12
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51-731-0
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Tocris Bioscience™
5173/10 		10 mg
Each for $265.64
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Description

Description

Potent and selective BRD4 bromodomain inhibitor (Ki = 30 - 50 nM for the first bromodomain (BRD4(1)). Exhibits 10-fold selectivity for BRD4(1) over BRD4(2). Blocks BRD4 transcriptional activity in lipopolysaccharide-induced production of both nitric oxide and IL-6 in mouse macrophages (IC50 values are 3.8 and 4.9 μM, respectively). Attenuates melanoma cell proliferation in vitro.
Specifications

Specifications

>98%
MS 436
383.42
MS 436
SDS
Documents

Documents

Product Certifications

For Research Use Only

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