Molecular Probes™ Tetramethylrhodamine (TAMRA) Alkyne (5-Carboxytetramethylrhodamine, Propargylamide), 5-isomer

Tetramethylrhodamine (TAMRA) Alkyne (5-Carboxytetramethylrhodamine, Propargylamide), 5-isomer

Supplier:  Molecular Probes™ T10183

Catalog No. T10183

Description

The red-fluorescent tetramethylrhodamine (TAMRA) alkyne can be reacted with azides via a copper-catalyzed click reaction. Click chemistry describes a class of chemical reactions that use bio-orthogonal or biologically unique moities to label and detect a molecule of interest using a two-step procedure. The two-step reaction procedure involves a copper-catalyzed triazole formation of an azide and an alkyne. Click reactions have several characteristics: the reaction between the detection moieties is efficient; no extreme temperatures or solvents are required; the reaction product is stable; the components of the reaction are bioinert; and perhaps most importantly, no side reactions occur – the label and detection tags react selectively and specifically with one another. Unlike traditional chemical reactions utilizing succinimidyl esters or maleimides that target amines and sulfhydryls – functional groups that are not unique – click chemistry-labeled molecules can be applied to complex biological samples and be detected with unprecedented sensitivity due to extremely low background.

Specifications

• Format: Solid
• Product Type: Tetramethylrhodamine Alkyne
• Solubility: DMSO (Dimethylsulfoxide)
• Chemical Reactivity: Azide
• Reactive Group: Alkyne
• Reactive Moiety: Alkyne
• Label Type: Classic Dyes
• Product Line: Molecular Probes™

• Quantity: 0.5 mg
• Molecular Weight (g/mol): 467.53 Da
• Content And Storage: Store at ≤-20°C, desiccated and protected from light.
• Detection Method: Fluorescent
• Shipping Condition: Room Temperature
• Label or Dye: TAMRA™ Isomers, TMR (Tetramethylrhodamine)
• Color: Orange

For Research Use Only. Not for use in diagnostic procedures.