Sulfamethoxazole, 98%, Thermo Scientific Chemicals

Description

Sulfamethoxazole, CAS # 723-46-6, is a sulfonamide antibiotic that inhibits folic acid synthesis in bacteria and prevents cell division and growth.

A broad spectrum bacteriostatic sulfonamide antibiotic

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Sulfamethoxazole is an antibiotic composed of an isoxazole with a 4-aminobenzenesulfonamido and methyl-group substitution at positions 5 and 3, respectively

• Sulfamethoxazole carries out most of its action through the inhibition of dihydropteroate synthase, the enzyme responsible for the synthesis of the precursor of folic acid; inhibition of folic acid synthesis prevents DNA replication and cell division in susceptible bacteria

Application

• Sulfamethoxazole can elicit an allergic response and may be useful for immune cell studies in laboratory settings

• Sulfamethoxazole is suitable for laboratory research on infection, environmental pollution, and the physiology of susceptible bacteria

Specifications

Chemical Identifiers

• CAS: 723-46-6
• Molecular Formula: C10H11N3O3S
• Molecular Weight (g/mol): 253.276
• MDL Number: MFCD00010546
• InChI Key: JLKIGFTWXXRPMT-UHFFFAOYSA-N
• Synonym: sulfamethoxazole, sulphamethoxazole, sulfisomezole, gantanol, sulfamethoxazol, metoxal, sulfamethylisoxazole, simsinomin, radonil, sinomin
• PubChem CID: 5329
• ChEBI: CHEBI:9332
• IUPAC Name: 4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide
• SMILES: CC1=CC(=NO1)NS(=O)(=O)C2=CC=C(C=C2)N

• Melting Point: 168°C to 172°C
• Boiling Point: 482°C
• Flash Point: >110°C (230°F)
• Packaging: Plastic bottle
• Quantity: 100 g
• Beilstein: 6732984
• Sensitivity: Light sensitive
• Solubility Information: Soluble in ethanol or acetone. Very slightly soluble in water
• Formula Weight: 253.28
• Percent Purity: 98%
• Physical Form: Powder
• Chemical Name or Material: Sulfamethoxazole

Safety and Handling

Hazard Category	H302-H315-H319-H335
Precautionary Statement	P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
EINECSNumber	211-963-3
RTECSNumber	WP0700000
TSCA	Yes
Recommended Storage	Keep cold

SDS

RUO – Research Use Only