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  8. SB 228357, Tocris Bioscience™

SB 228357, Tocris Bioscience™

Catalog Number 137550
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
181629-93-6
C22H17F4N3O2
431.391
RRJLJKRFFRZRAF-UHFFFAOYSA-N
unii-5rdn2e8e97, tocris-1375, chembl14276, n-3-fluoro-5-3-pyrindyl phenyl-2,3-dihydro-5-methoxy-6-trifluoromethyl-1h-indole-1-carboxamide, n-3-fluoro-5-pyridin-3-ylphenyl-5-methoxy-6-trifluoromethyl-2,3-dihydroindole-1-carboxamide, n-3-fluoro-5-3-pyridinyl phenyl-2,3-dihydro-5-methoxy-6-trifluoromethyl-1h-indole-1-carboxamide, lopac-s-2318, d05nwh, gtpl192, n-3-3-pyridinyl-5-fluorophenyl-5-methoxy-6-trifluoromethyl indoline-1-carboxamide
443390
CHEBI:8979
N-(3-fluoro-5-pyridin-3-ylphenyl)-5-methoxy-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
COC1=C(C=C2C(=C1)CCN2C(=O)NC3=CC(=CC(=C3)C4=CN=CC=C4)F)C(F)(F)F
This item is not returnable. View return policy
181629-93-6
C22H17F4N3O2
431.391
RRJLJKRFFRZRAF-UHFFFAOYSA-N
unii-5rdn2e8e97, tocris-1375, chembl14276, n-3-fluoro-5-3-pyrindyl phenyl-2,3-dihydro-5-methoxy-6-trifluoromethyl-1h-indole-1-carboxamide, n-3-fluoro-5-pyridin-3-ylphenyl-5-methoxy-6-trifluoromethyl-2,3-dihydroindole-1-carboxamide, n-3-fluoro-5-3-pyridinyl phenyl-2,3-dihydro-5-methoxy-6-trifluoromethyl-1h-indole-1-carboxamide, lopac-s-2318, d05nwh, gtpl192, n-3-3-pyridinyl-5-fluorophenyl-5-methoxy-6-trifluoromethyl indoline-1-carboxamide
443390
CHEBI:8979
N-(3-fluoro-5-pyridin-3-ylphenyl)-5-methoxy-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
COC1=C(C=C2C(=C1)CCN2C(=O)NC3=CC(=CC(=C3)C4=CN=CC=C4)F)C(F)(F)F

Description

5-HT2C/2B antagonist/inverse agonist

5-HT2C/2B receptor antagonist (pKi values are 7.0, 8.1 and 9.1 at 5-HT2A, 2B and 2C receptors respectively). Displays inverse agonism in a 5-HT-stimulated PI hydrolysis model of 5-HT2C receptor function. Orally active in vivo.
Quantity 50 mg
Formula Weight 431.39
Percent Purity >99%
Chemical Name or Material SB 228357

Safety and Handling

Recommended Storage Store at Room Temperature
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