Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Benzenoids
  6. Benzene and substituted derivatives
  7. N-phenylureas
  8. SB 225002, Tocris Bioscience™

SB 225002, Tocris Bioscience™

Catalog Number 272550
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
182498-32-4
C13H10BrN3O4
352.14
MFCD00954637
MQBZVUNNWUIPMK-UHFFFAOYSA-N
1-2-bromophenyl-3-2-hydroxy-4-nitrophenyl urea, n-2-bromophenyl-n'-2-hydroxy-4-nitrophenyl urea, 3-2-bromophenyl-1-2-hydroxy-4-nitrophenyl urea, n-2-hydroxy-4-nitrophenyl-n′-2-bromophenyl urea, d0e9bu, d0f6wv, d0t2ad, gtpl833, n-2-hydroxy-4-nitrophenyl-n'-2-bromophenyl urea, p 1-6-hydroxymethylpterin-p 2-5'-adenosyl diphosphate
3854666
3-(2-bromophenyl)-1-(2-hydroxy-4-nitrophenyl)urea
OC1=C(NC(=O)NC2=CC=CC=C2Br)C=CC(=C1)[N+]([O-])=O
This item is not returnable. View return policy
182498-32-4
C13H10BrN3O4
352.14
MFCD00954637
MQBZVUNNWUIPMK-UHFFFAOYSA-N
1-2-bromophenyl-3-2-hydroxy-4-nitrophenyl urea, n-2-bromophenyl-n'-2-hydroxy-4-nitrophenyl urea, 3-2-bromophenyl-1-2-hydroxy-4-nitrophenyl urea, n-2-hydroxy-4-nitrophenyl-n′-2-bromophenyl urea, d0e9bu, d0f6wv, d0t2ad, gtpl833, n-2-hydroxy-4-nitrophenyl-n'-2-bromophenyl urea, p 1-6-hydroxymethylpterin-p 2-5'-adenosyl diphosphate
3854666
3-(2-bromophenyl)-1-(2-hydroxy-4-nitrophenyl)urea
OC1=C(NC(=O)NC2=CC=CC=C2Br)C=CC(=C1)[N+]([O-])=O

Description

Potent and selective CXCR2 antagonist

Potent and selective CXCR2 chemokine receptor antagonist (IC50 = 22 nM) that displays > 150-fold selectivity over CXCR1 receptors. Causes inhibition of IL-8 and GROα-mediated calcium mobilization in HL60 cells (IC50 values are 8 and 10 nM respectively). Prevents IL-8-induced neutrophil chemotaxis in vitro and sequestration in vivo. Inhibits HIV replication in lymphocytes and macrophages.
Quantity 50 mg
Formula Weight 352.14
Percent Purity >99%
Chemical Name or Material SB 225002

Safety and Handling

Recommended Storage Store at Room Temperature
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit