(S)-(+)-Epichlorohydrin, 98+%, Thermo Scientific Chemicals

Description

(S)-(+)-Epichlorohydrin is utilized for the synthesis of macquarimicins and hydroxyisoxazolidines and (+)-cis-sylvaticin, which is a potential antitumor agent. It is used to synthesize inhibitors of fatty acid oxidation as potential metabolic modulators. It acts as a solvent for natural and synthetic resins, gums, cellulose esters and ethers, paints, varnishes, nail enamels, lacquers and cement for celluloid. It is also used as a stabilizer and also useful as a bifunctional alkylating agent with the potential to form DNA cross-links.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
(S)-(+)-Epichlorohydrin is utilized for the synthesis of macquarimicins and hydroxyisoxazolidines and (+)-cis-sylvaticin, which is a potential antitumor agent. It is used to synthesize inhibitors of fatty acid oxidation as potential metabolic modulators. It acts as a solvent for natural and synthetic resins, gums, cellulose esters and ethers, paints, varnishes, nail enamels, lacquers and cement for celluloid. It is also used as a stabilizer and also useful as a bifunctional alkylating agent with the potential to form DNA cross-links.

Solubility
Miscible with chloroform and methanol. Immiscible with water.

Notes
Hygroscopic. Store in a cool place. Incompatible with acids, bases, ammonia, amines, sodium and sodium oxides, zinc, magnesium, aluminum and its alloys and halides.

Specifications

Chemical Identifiers

• CAS: 67843-74-7
• Molecular Formula: C3H5ClO
• Molecular Weight (g/mol): 92.52
• MDL Number: MFCD00077760
• InChI Key: BRLQWZUYTZBJKN-GSVOUGTGSA-N
• Synonym: s-+-epichlorohydrin, s-epichlorohydrin, 2s-2-chloromethyl oxirane, s-chloromethyl oxirane, s-3-chloropropylene oxide, s-2-chloromethyl oxirane, epichlorohydrin, +, unii-scr89b4r6o, ccris 6388
• PubChem CID: 149428
• ChEBI: CHEBI:37145
• IUPAC Name: (2S)-2-(chloromethyl)oxirane
• SMILES: ClC[C@@H]1CO1

• Density: 1.18
• Boiling Point: 116°C to 117°C
• Flash Point: 32°C (90°F)
• Refractive Index: 1.438
• Quantity: 25 g
• UN Number: UN2023
• Beilstein: 1420784
• Solubility Information: Miscible with chloroform and methanol. Immiscible with water.
• Optical Rotation: +35° (c=1 in Methanol)
• Formula Weight: 92.53
• Percent Purity: ≥98%
• Chemical Name or Material: (S)-(+)-Epichlorohydrin

Safety and Handling

Hazard Category	H226-H301+H311+H331-H314-H317-H350
Hazard Statement	GHS H Statement H300-H310-H330-H350-H314-H318-H226-H317 Fatal if swallowed. Fatal in contact with skin. Fatal if inhaled. May cause cancer. Causes severe skin burns and eye damage. Causes serious eye damage. Flammable liquid and vapor. May cause an allergic skin reaction.
Precautionary Statement	P201-P202-P210-P233-P235-P240-P241-P242-P243-P260-P264b-P270-P271-P272-P280g-P281-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P333+P313-P363-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: II; Proper Shipping Name: EPICHLOROHYDRIN
RTECSNumber	RR0427100
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only