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  7. Rifabutin, 98%, Thermo Scientific Chemicals

Rifabutin, 98%, Thermo Scientific Chemicals

Catalog No. AC461210050
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Quantity:
1 g
5 g

Description

Rifabutin, CAS # 72559-06-09, is a broad-spectrum antibiotic with activity against mycobacteria, gram-positive and gram-negative bacteria.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description
Rifabutin is a compound with antibacterial activity most commonly used against Mycobacterium tuberculosis
Rifabutin is a derivative of Rifamycin S that acts through blocking RNA polymerase subunit beta (RpoB)
Rifabutin is an inducer as well as a substrate of CYP3A, a cytochrome P450 enzyme
Applications
Rifabutin may be used in pharmacokinetic laboratory studies and high-throughput drug screens
May be used in laboratory studies to determine drug resistance mutations present in Mycobacterium tuberculosis strains
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 72559-06-9
Molecular Formula C46H62N4O11
Molecular Weight (g/mol) 847.02
MDL Number MFCD00866816
InChI Key ATEBXHFBFRCZMA-VXTBVIBXSA-N
Synonym rifabutin, ansamycin, rifabutine, mycobutin, ansatipine, ansatipin, alfacid, rifabutina, rifabutinum, antibiotic lm 427
PubChem CID 57448257
IUPAC Name (7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17-trihydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-1'-(2-methylpropyl)-6,23,32-trioxo-8,33-dioxa-24,27,29-triazaspiro[pentacyclo[23.6.1.1⁴,⁷.0⁵,³¹.0²⁶,³⁰]tritriacontane-28,4'-piperidin]-1,3,5(31),9,19,21,25,29-octaen-13-yl acetate
SMILES CO[C@H]1\C=C\O[C@@]2(C)OC3=C(C)C(O)=C4C(=O)C(NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)=C1NC5(CCN(CC(C)C)CC5)N=C1C4=C3C2=O

Specifications

Assay Percent Range 97.5% min. (HPLC)
Quantity 5 g
Formula Weight 847
Percent Purity 98%
Chemical Name or Material Rifabutin

Safety and Handling

Hazard Category GHS Signal Word: Warning
SDS

RUO – Research Use Only

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