Thermo Scientific™ EGS (ethylene glycol bis(succinimidyl succinate))

Crosslink amines to amines with this membrane permeable crosslinker composed of NHS-ester groups and a 16.1A hydroxylamine-cleavable spacer arm.

Supplier:  Thermo Scientific™ 21565

Catalog No. PI21565

Description

Thermo Scientific™ Pierce EGS is a crosslinker that contains amine-reactive NHS-ester ends around a 12-atom spacer arm, which can be cleaved by treatment with hydroxylamine at pH 8.5.

Highlights:

• Cleavable at pH 8.5 using Hydroxylamine for 3-6 hours at 37°C
• Lactose dehydrogenase retained 60% of its activity after reversible crosslinking with EGS
• Reactive groups: NHS esters (homobifunctional)
• Reactive toward: amino groups

Specifications

• Chemical Reactivity: Amine-Amine
• Description: EGS
• PEGylated: No
• Content And Storage: Upon receipt store at 4°C.
• Shipping Condition: Ambient
• Labeling Method: Chemical Labeling
• Reactive Moiety: NHS Ester
• Form: Powder
• Solubility: DMF, DMSO
• Water Soluble: No

• Cleavable: By Hydroxylamine
• Molecular Weight (g/mol): 456.36
• Spacer Arm Length: 16.1 Å
• Cell Permeability: Yes
• Product Line: Pierce™
• Crosslinker Type: Homobifunctional
• Spacer: Medium (10 to 30 Å)
• Quantity: 1 g
• Format: Standard
• Product Type: Crosslinker

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov

For Research Use Only. Not for use in diagnostic procedures.