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Tocris Bioscience™ PD 98059
MEK inhibitor
Specifications
| Purity | 98% |
|---|---|
| Molecular Formula | 2-(2-Amino-3-methoxyphenyl)-4 H-1-benzopyran-4-one |
| CAS | 167869-21-8 |
| Content And Storage | Room Temperature |
| Product Type | PD 98059 |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|
12-131
|
Tocris Bioscience™
1213/1 |
1 mg |
Each for $112.52
|
N/A | |||||
|
12-135-0R
|
Tocris Bioscience™
1213/50 |
50 mg |
Each for $988.32
|
N/A | |||||
|
12-131-0
|
Tocris Bioscience™
1213/10 |
10 mg |
Each for $237.80
|
N/A | |||||
Description
Inhibitor of mitogen-activated protein kinase kinase (MKK/ MEK). Acts by binding to the inactivated form of MEK, thereby preventing its phosphorylation by cRAF or MEK kinase (IC50 = 2-7 μM). Inhibits cell growth and proliferation in acute myelogenous leukemia (AML) cell lines; causes G1 arrest by blocking p53-dependent p21 induction. Enhances embryonic stem cell self-renewal.Specifications
| 98% | |
| 167869-21-8 | |
| PD 98059 | |
| PD 98059 |
| 2-(2-Amino-3-methoxyphenyl)-4 H-1-benzopyran-4-one | |
| Room Temperature | |
| M.W. (Observed): 267.28 |
For Research Use Only
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