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Methyl piperidine-4-carboxylate, 98%, Thermo Scientific Chemicals

Catalog Number AAH6175422
Click to view available options
Quantity:
25 g
100 g
2971-79-1
C7H13NO2
143.19
MFCD00190578
RZVWBASHHLFBJF-UHFFFAOYSA-N
methyl isonipecotate, methyl 4-piperidinecarboxylate, 4-piperidinecarboxylic acid, methyl ester, piperidine-4-carboxylic acid methyl ester, 4-piperidinecarboxylic acid methyl ester, isonipecotic acid methyl ester, methylpiperidine-4-carboxylate, methylisonipecotate, methyl piperidin-4-carboxylate, acmc-20aiv4
424914
methyl piperidine-4-carboxylate
COC(=O)C1CCNCC1
2971-79-1
C7H13NO2
143.19
MFCD00190578
RZVWBASHHLFBJF-UHFFFAOYSA-N
methyl isonipecotate, methyl 4-piperidinecarboxylate, 4-piperidinecarboxylic acid, methyl ester, piperidine-4-carboxylic acid methyl ester, 4-piperidinecarboxylic acid methyl ester, isonipecotic acid methyl ester, methylpiperidine-4-carboxylate, methylisonipecotate, methyl piperidin-4-carboxylate, acmc-20aiv4
424914
methyl piperidine-4-carboxylate
COC(=O)C1CCNCC1

Methyl piperidine-4-carboxylate is a reactant for C-2 arylation of piperidines through directed transition metal-catalyzed sp3 C-H activation. It is used as a reactant for synthesis of antitubercular agents, aminopyrazine inhibitors, orally available naphthyridine protein kinase D inhibitors and a scalable catalyst from asymmetric hydrogenation of sterically demanding aryl enamide.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Methyl piperidine-4-carboxylate is a reactant for C-2 arylation of piperidines through directed transition metal-catalyzed sp3 C-H activation. It is used as a reactant for synthesis of antitubercular agents, aminopyrazine inhibitors, orally available naphthyridine protein kinase D inhibitors and a scalable catalyst from asymmetric hydrogenation of sterically demanding aryl enamide.

Solubility
Slightly soluble in water.

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.
TRUSTED_SUSTAINABILITY
Color Colorless to Yellow
Density 1.06 g/mL
Boiling Point 85°C to 90°C
Flash Point 89°C (192°F)
Refractive Index 1.465
Quantity 100 g
Beilstein 224128
Solubility Information Slightly soluble in water.
Formula Weight 143.18
Percent Purity 98%
Physical Form Liquid
Chemical Name or Material Methyl piperidine-4-carboxylate
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Hazard Category H227-H314-H335
Hazard Statement GHS H Statement
H315-H319-H335-H227
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Combustible liquid.
Precautionary Statement P210-P235-P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c
DOTInformation Hazard Class: 8; Packaging Group: III
TSCA No
Recommended Storage Ambient temperatures

RUO – Research Use Only

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