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Molecular Probes™ Iodoacetamide Azide
iodoacetamide azide
Supplier: Molecular Probes™ I10188
Description
Conjugates prepared with the thiol-reactive azide, succinimidyl ester can be detected with an alkyne-containing molecule in a click chemistry reaction. Click chemistry describes a class of chemical reactions that use bio-orthogonal or biologically unique moities to label and detect a molecule of interest using a two-step procedure. The two-step reaction procedure involves a copper-catalyzed triazole formation of an azide and an alkyne. Click reactions have several characteristics: the reaction between the detection moieties is efficient; no extreme temperatures or solvents are required; the reaction product is stable; the components of the reaction are bioinert; and perhaps most importantly, no side reactions occur – the label and detection tags react selectively and specifically with one another. Unlike traditional chemical reactions utilizing succinimidyl esters or maleimides that target amines and sulfhydryls – functional groups that are not unique – click chemistry-labeled molecules can be applied to complex biological samples and be detected with unprecedented sensitivity due to extremely low background.Specifications
Solid | |
Iodoacetamide Azide | |
DMSO (Dimethylsulfoxide) | |
Thiol | |
Room Temperature | |
Azide | |
Molecular Probes™ |
1 mg | |
310.14 Da | |
Store at ≤-20°C, desiccated and protected from light. | |
Iodoacetamide | |
Alkyl Halide, Iodoacetamide | |
Click Chemistry Label |
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Product Title
For Research Use Only. Not for use in diagnostic procedures.
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