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IEM 1460, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
Voltage-dependent open-channel blocker of AMPA receptors. Selective for GluR2 subunit-lacking (Ca2+-permeable) receptors over GluA2-containing receptors (IC50 values are 2.6 and 1102 μM, respectively). Selectively blocks fast spiking interneuron but not medium spiny projection neuron in mouse striatum. Also blocks NMDA receptor-mediated currents. Anticonvulsant in vivo.
Specifications
Specifications
Quantity | 50 mg |
Formula Weight | 454.33 |
Percent Purity | >98% |
Chemical Name or Material | IEM 1460 |
Safety and Handling
Recommended Storage | Desiccate at Room Temperature |
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