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Hesperadin hydrochloride, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
ATP-competitive inhibitor of Aurora B kinase (IC50 = 250 nM). Prevents chromosome alignment and segregation; also induces polyploidy and prevents histone H3-Ser10 phosphorylation. Overrides the spindle assembly checkpoint and induces mitotic exit in monastrol - and taxol -treated HeLa cells.
Specifications
Quantity | 50 mg |
Formula Weight | 553.12 |
Percent Purity | >99% |
Chemical Name or Material | Hesperadin hydrochloride |
Safety and Handling
Recommended Storage | Desiccate at Room Temperature |
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