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GYKI 52466 dihydrochloride, Tocris Bioscience™

Catalog Number 145450
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
2319722-40-0
C17H15N3O2
293.326
LFBZZHVSGAHQPP-UHFFFAOYSA-N
unii-471v8nz5x3, 1-p-aminophenyl-4-methyl-7,8-methylenedioxy-5h-2,3-benzodiazepine hydrochloride, 4-8-methyl-9h-1,3 dioxolo 4,5-h 2,3 benzodiazepin-5-yl aniline, 4-8-methyl-9h-1,3-dioxolo 4,5-h 2,3 benzodiazepin-5-yl benzenamine, benzenamine, 4-8-methyl-9h-1,3-dioxolo 4,5-h 2,3 benzodiazepin-5-yl, benzenamine,4-8-methyl-9h-1,3-dioxolo 4,5-h 2,3 benzodiazepin-5-yl, 1-4-aminophenyl-4-methyl-7,8-methylenedioxy-5h-2,3-benzodiazepine, gyki 52466 dihydrochloride, 4-8-methyl-9h-1,3 dioxolo 4',5':4,5 benzo 1,2-d 1,2 diazepin-5-yl aniline
3538
CHEBI:79560
4-(8-methyl-9H-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-5-yl)aniline
CC1=NN=C(C2=CC3=C(C=C2C1)OCO3)C4=CC=C(C=C4)N
This item is not returnable. View return policy
2319722-40-0
C17H15N3O2
293.326
LFBZZHVSGAHQPP-UHFFFAOYSA-N
unii-471v8nz5x3, 1-p-aminophenyl-4-methyl-7,8-methylenedioxy-5h-2,3-benzodiazepine hydrochloride, 4-8-methyl-9h-1,3 dioxolo 4,5-h 2,3 benzodiazepin-5-yl aniline, 4-8-methyl-9h-1,3-dioxolo 4,5-h 2,3 benzodiazepin-5-yl benzenamine, benzenamine, 4-8-methyl-9h-1,3-dioxolo 4,5-h 2,3 benzodiazepin-5-yl, benzenamine,4-8-methyl-9h-1,3-dioxolo 4,5-h 2,3 benzodiazepin-5-yl, 1-4-aminophenyl-4-methyl-7,8-methylenedioxy-5h-2,3-benzodiazepine, gyki 52466 dihydrochloride, 4-8-methyl-9h-1,3 dioxolo 4',5':4,5 benzo 1,2-d 1,2 diazepin-5-yl aniline
3538
CHEBI:79560
4-(8-methyl-9H-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-5-yl)aniline
CC1=NN=C(C2=CC3=C(C=C2C1)OCO3)C4=CC=C(C=C4)N

Selective non-competitive AMPA antagonist

GYKI 52466 dihydrochloride is a selective noncompetitive AMPA receptor antagonist (IC50 values are 10-20, ∼ 450 and >50 μM for AMPA-, kainate- and NMDA-induced responses respectively). Skeletal muscle relaxant and orally-active anticonvulsant. Has anti-proliferative effects in transformed cells.
Quantity 50 mg
Formula Weight 366.24
Percent Purity >99%
Chemical Name or Material GYKI 52466 dihydrochloride
Recommended Storage Desiccate at Room Temperature
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