Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Tocris Bioscience™ GSK 1838705
Potent IR and IGF1R inhibitor; also inhibits anaplastic lymphoma kinase (ALK)
$397.88 - $1639.08
Specifications
| Purity | >98% |
|---|---|
| Product Type | GSK 1838705 |
| Molecular Weight (g/mol) | 532.57 |
| Inhibitors | GSK 1838705 |
Description
Potent insulin receptor (IR) and insulin-like growth factor-1 receptor (IGF1R) inhibitor (IC50 values are 1.6 and 2 nM, respectively). Also inhibits anaplastic lymphoma kinase (ALK) (IC50 = 0.5 nM). Displays > 800-fold selectivity for IR, IGFR1 and ALK over a panel of 44 kinases including JNK. Blocks proliferation of cancer cell lines in vitro, and causes complete regression of ALK-dependent tumors in vivo. Orally bioavailable.Specifications
| >98% | |
| GSK 1838705 | |
| 532.57 | |
| GSK 1838705 |
For Research Use Only
Spot an opportunity for improvement?
Provide Content Correction
Provide Content Correction
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Product Title