Ethyl bromoacetate, 98%, Thermo Scientific Chemicals

Description

Ethyl bromoacetate is widely used as an alkylating reagent involved in the Reformatsky reaction to prepare the beta-hydroxy esters by reacting with carbonyl compounds. It is also used for the syntheses of witting reagent, artificial diethylstilbestrol antigen, 3-phenyl-1-naphthol and steroidal thiazolidinone derivatives. It finds applications in the preparation of reversibly photoresponsive coumarin-stabilized polymeric nanoparticles in an aqueous medium which act as a detectable drug carrier.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Ethyl bromoacetate is widely used as an alkylating reagent involved in the Reformatsky reaction to prepare the beta-hydroxy esters by reacting with carbonyl compounds. It is also used for the syntheses of witting reagent, artificial diethylstilbestrol antigen, 3-phenyl-1-naphthol and steroidal thiazolidinone derivatives. It finds applications in the preparation of reversibly photoresponsive coumarin-stabilized polymeric nanoparticles in an aqueous medium which act as a detectable drug carrier.

Solubility
Miscible with ethanol, acetone, benzene and ethyl ether. Immiscible with water.

Notes
It is a lachrymator. Incompatible with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 105-36-2
• Molecular Formula: C4H7BrO2
• Molecular Weight (g/mol): 167.002
• MDL Number: MFCD00000191
• InChI Key: PQJJJMRNHATNKG-UHFFFAOYSA-N
• Synonym: ethyl bromoacetate, antol, ethyl bromacetate, bromoacetic acid ethyl ester, ethyl monobromoacetate, acetic acid, bromo-, ethyl ester, ethoxycarbonylmethyl bromide, bromoacetic acid, ethyl ester, ethyl alpha-bromoacetate, ethyl bromo acetate
• PubChem CID: 7748
• IUPAC Name: ethyl 2-bromoacetate
• SMILES: CCOC(=O)CBr

• Melting Point: °C to 38°C
• Density: 1.506 g/mL
• Boiling Point: 159°C
• Flash Point: 47°C (117°F)
• Assay Percent Range: 98%
• Refractive Index: 1.451
• Linear Formula: BrCH₂CO₂CH₂CH₃
• Quantity: 100 g
• UN Number: UN1603
• Solubility Information: Miscible with ethanol,acetone,benzene and ethyl ether. Immiscible with water.
• Formula Weight: 167
• Percent Purity: 98%
• Chemical Name or Material: Ethyl bromoacetate

Safety and Handling

Hazard Category	H226-H300+H310+H330
Hazard Statement	GHS H Statement H300-H310-H330-H226
Precautionary Statement	P210-P233-P235-P240-P241-P242-P243-P260-P262-P264b-P270-P271-P280-P284-P301+P310-P303+P361+P353-P304+P340-P310-P330-P363-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: II; Proper Shipping Name: ETHYL BROMOACETATE
EINECSNumber	203-290-9
RTECSNumber	AF6000000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only