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Thermo Scientific™ DSS (disuccinimidyl suberate), No-Weigh™ Format

Crosslink amines to amines with disuccinimidyl suberate composed of NHS-ester groups with a membrane-permeable, mid-length spacer for intracellular protein crosslinking.

Supplier:  Thermo Scientific™ A39267

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Catalog No. PIA39267


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Description

Description

Thermo Scientific™ Pierce DSS, also called disuccinimidyl suberate, is noncleavable and membrane permeable crosslinker that contains an amine-reactive N-hydroxysuccinimide (NHS) ester at each end of an 8-carbon spacer arm.

  • Reactive groups: NHS ester (both ends)
  • Reactive towards: amino groups (primary amines)
  • Amine reactive sulfo-NHS ester reacts rapidly with any primary amine-containing molecule
  • Membrane-permeable, allowing for intracellular crosslinking
  • High purity, crystalline reagent can be used to create high-purity conjugates
  • Non-cleavable
  • Water-insoluble (dissolve first in DMF or DMSO); compare to BS3 (Sulfo-DSS)
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Amine-Amine
DSS
No
Upon receipt store desiccated at 4°C.
Ambient
Chemical Labeling
NHS Ester
Solid
DMF, DMSO
No
No
368.35
11.4 Å
Yes
No-Weigh™
Homobifunctional
Medium (10 to 30 Å)
10 x 2 mg
Standard, Single-use
Crosslinker
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