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Cyclophosphamide, Tocris Bioscience™

Catalog Number 409150
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Quantity:
50 mg
This item is not returnable. View return policy
50-18-0
C7H15Cl2N2O2P
261.083
CMSMOCZEIVJLDB-UHFFFAOYSA-N
cyclophosphamide, cyclophosphamid, cyclophosphane, cytophosphan, procytox, clafen, cytoxan, endoxan, neosar, cyclophosphamidum
2907
CHEBI:4027
N,N-bis(2-chloroethyl)-2-oxo-1,3,2$l^{5}-oxazaphosphinan-2-amine
C1CNP(=O)(OC1)N(CCCl)CCCl
This item is not returnable. View return policy
50-18-0
C7H15Cl2N2O2P
261.083
CMSMOCZEIVJLDB-UHFFFAOYSA-N
cyclophosphamide, cyclophosphamid, cyclophosphane, cytophosphan, procytox, clafen, cytoxan, endoxan, neosar, cyclophosphamidum
2907
CHEBI:4027
N,N-bis(2-chloroethyl)-2-oxo-1,3,2$l^{5}-oxazaphosphinan-2-amine
C1CNP(=O)(OC1)N(CCCl)CCCl

Description

Alkylating agent; chemotherapeutic

Nitrogen mustard alkylating agent and prodrug. Phosphoramide mustard (active metabolite) forms DNA cross-links leading to cell death. Inhibits aldehyde dehydrogenase 1 (ALDH1) through its degradation product acrolein. Chemotherapeutic for the treatment of breast cancer; regulates Bax and Bcl-2 expression when administered with etoposide (Cat. No. 1226) in breast cancer cell lines.
Quantity 50 mg
Formula Weight 261.09
Percent Purity >99%
Chemical Name or Material Cyclophosphamide

Safety and Handling

Recommended Storage Store at -20°C
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