5-Iodo-2'-deoxycytidine, 99%, Thermo Scientific Chemicals

Description

5-Iodo-2'-deoxycytidine is used in the construction of DNA oligomers to enable structural studies and photoactivated cross-linking. It is used in the synthesis of other modified nucleosides, such as 5-ethynylferrocenyl-2?-deoxycytidine used in semiconductor electrodes and 10-(2-deoxyβ-D-ribofuranosyl)pyrimido[4,5:4,5]pyrimido[1,6-a]indole-6,9(7H)-dione (dCPPI).

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
5-Iodo-2′-deoxycytidine is used in the construction of DNA oligomers to enable structural studies and photoactivated cross-linking. It is used in the synthesis of other modified nucleosides, such as 5-ethynylferrocenyl-2′-deoxycytidine used in semiconductor electrodes and 10-(2-deoxyβ-D-ribofuranosyl)pyrimido[4′,5′:4,5]pyrimido[1,6-a]indole-6,9(7H)-dione (dCPPI).

Solubility
Slightly soluble in water.

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents and heat.

Specifications

Chemical Identifiers

• CAS: 611-53-0
• Molecular Formula: C9H12IN3O4
• Molecular Weight (g/mol): 353.12
• MDL Number: MFCD00038063
• InChI Key: WEVJJMPVVFNAHZ-RRKCRQDMSA-N
• Synonym: 5-iodo-2'-deoxycytidine, ibacitabine, 2'-deoxy-5-iodocytidine, 4-amino-1-2r,4s,5r-4-hydroxy-5-hydroxymethyl tetrahydrofuran-2-yl-5-iodopyrimidin-2 1h-one, ibacitabine inn, ibacitabinum latin, ibacitabina spanish, cytidine, 2'-deoxy-5-iodo, iododeoxycytidine, unii-3ek8532dzv
• PubChem CID: 65050
• IUPAC Name: 4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidin-2-one
• SMILES: NC1=NC(=O)N(C=C1I)[C@H]1C[C@H](O)[C@@H](CO)O1

• Melting Point: 180°C to 183°C
• Color: White
• Quantity: 2 g
• Solubility Information: Slightly soluble in water.
• Formula Weight: 353.11
• Percent Purity: 99%
• Physical Form: Powder
• Chemical Name or Material: 5-Iodo-2'-deoxycytidine

Safety and Handling

Hazard Category	Acute toxicity (category 4)
Hazard Statement	Harmful if swallowed
EINECSNumber	210-269-8
TSCA	No
Recommended Storage	Store at -20°C

SDS

RUO – Research Use Only